Gestational diabetes & diabetes in pregnancy
Higher prevalence of gestational diabetes in euthyroid women with thyroid autoimmunity who were expecting a female fetus
Authors' conclusion
The prevalence of GDM was increased in euthyroid TAI+ women, but only in the case of pregnancies with a FF. This is opposite to the result observed in the general population and deserves more research to explore the underlying mechanisms.
Study context
- Population
- Pregnant women screened at median 12 (11–14) weeks for thyroid disorders (TSH, FT4, TPOAb) and at 24–28 weeks for gestational diabetes mellitus (GDM) by OGTT; excluded pre-pregnancy DM or hypertension, thyroid dysfunction, thyroid screening after 20 weeks, assisted pregnancies; 622 female fetus (FF), 579 male fetus (MF)
- Participants
- 1,201 women
- Exposure
- Euthyroid women with TAI vs without TAI, by fetal sex
- TAI+n = 75
- Outcome
- GDM (2013 WHO criteria)
- Follow-up
- 24-28 weeks
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
GDM prevalence
P = 0.008 after adjustment for confounders
- Overall GDM prevalence
- 19.6%
Observational data: associations, not effects.
Further findings
GDM prevalence, women expecting a FF
P = 0.002
Original publication
Higher prevalence of gestational diabetes in euthyroid women with thyroid autoimmunity who were expecting a female fetus. Eur Thyroid J. Published 31 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →