Higher HbA1c Following Younger Age of Transfer From Pediatric to Adult Type 1 Diabetes Services: Data From the Australasian Diabetes Data Network (ADDN) Registry
Authors' conclusion
Early transfer from pediatric to adult T1D services was associated with higher HbA1c in real-world settings.
Study context
- Population
- Youth with T1D transferred from pediatric to adult services 2013–2022, Australasian Diabetes Data Network (ADDN) registry; 49.7% male; mean transfer age 18.1 ± 1.4 years
- Participants
- 784 participants
- Exposure
- Early vs later transfer from pediatric to adult T1D services
- Early transferersn = 342
- Late transferersn = 442reference
- Outcome
- Adult-service HbA1c and associated factors
Methodological detailsmultivariable generalized estimating equations
- Multivariable generalized estimating equations
Main finding
As reported in the abstract
HbA1c at first adult visit
| Group | Value | Mmol/mol |
|---|---|---|
| Early transferers | mean 9.3 (SD 1.9) % | 78.2 ± 20.6 |
| Late transferers | mean 8.8 (SD 1.9) % | 72.9 ± 20.4 |
Value
Early transferersmean 9.3 (SD 1.9) %
Late transferersmean 8.8 (SD 1.9) %
Mmol/mol
Early transferers78.2 ± 20.6
Late transferers72.9 ± 20.4
- Early transferers vs Late transferers: P = 0.01
Observational data: associations, not effects.
Further findings
Factors associated with higher adult-service HbA1c (multivariable generalized estimated equations (GEEs))
| β (95% CI) | P value | |
|---|---|---|
| Transfer age (younger) | −0.15 (−0.30 to −0.002) | P = 0.047 |
| Socioeconomic disadvantage | 0.58 (0.10–1.06) | P = 0.02 |
| Mean HbA1c in 36 months before transfer | 0.06 (0.04–0.07) | P < 0.001 |
Gap between last pediatric and first adult visit
P < 0.001
Mean
| Outcome | Early transferers | Late transferers | P value |
|---|---|---|---|
| Socioeconomic disadvantage score at first adult visit | 976.8 (SD 101.7) | 992.8 (SD 81.1) | P = 0.03 |
Original publication
Higher HbA1c Following Younger Age of Transfer From Pediatric to Adult Type 1 Diabetes Services: Data From the Australasian Diabetes Data Network (ADDN) Registry. Diabetes Care. Published 28 May 2026. doi:10. 2337/ dc25-3026
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