Demographic, Clinical, Management, and Outcome Characteristics of 8,004 Young Children With Type 1 Diabetes
Authors' conclusion
Across three major registries, more than half of children age <6 years did not achieve the target HbA1c of <7.0% (53 mmol/mol). CGM was used by most participants, whereas insulin pump use varied across registries, and HCL system use was rare. The differences seen in glycemia and use of diabetes technologies among registries require further investigation to determine potential contributing factors and areas to target to improve the care of this vulnerable group.
Study context
- Population
- Children with T1D aged <6 years in three international registries, 2019–2021
- Participants
- 8,004 children
- Exposure
- DPV vs T1DX-QI vs Australasian Diabetes Data Network (ADDN)
- Outcome
- HbA1c
Methodological detailsthree international registries, prospective registry data 2019-2021
- Three international registries
- Prospective registry data 2019-2021
Main finding
As reported in the abstract
HbA1c
HbA1c mmol/mol DPV 56 ± 10 · T1DX-QI 64 ± 16 · ADDN 61 ± 13
HbA1c <7.0% achieved DPV 43.6% · T1DX-QI 25.5% · ADDN 27.5%
- Overall achieved target HbA1c <7.0% (53 mmol/mol)
- 37.5%
Observational data: associations, not effects.
Further findings
Age at diagnosis
Diabetes duration
BMI z score in overweight range
Insulin pump use
CGM use
| Outcome | DPV | T1DX-QI | ADDN |
|---|---|---|---|
| HCL use | 6.9% | — not stated in the abstract | 0.5% |
— not stated in the abstract
Hybrid closed-loop (HCL) use
- HCL use uncommon
Original publication
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