High cereal fibre but not total fibre is associated with a lower risk of type 2 diabetes: Evidence from the Melbourne Collaborative Cohort Study
Authors' conclusion
Intake of cereal fibre and, to a lesser extent, fruit fibre, may reduce the risk of diabetes, while total fibre showed no association. Our data suggest that specific recommendations regarding dietary fibre intake may be needed to prevent diabetes.
Study context
- Population
- Adults aged 40 to 69 years enrolled 1990–1994 in the Melbourne Collaborative Cohort Study; mean follow-up 13.8 years39,185 analysed
- Participants
- 41,513 adults
- Exposure
- Quintiles of dietary fibre intake
- Outcome
- Self-reported incident diabetes
- Follow-up
- Mean 13.8 years
Methodological detailsquintiles of fibre intake, modified Poisson regression, adjusted for dietary, lifestyle, obesity, socioeconomic and other confounders
- Quintiles of fibre intake
- Modified Poisson regression
- Adjusted for dietary, lifestyle, obesity, socioeconomic and other confounders
Main finding
As reported in the abstract
Incident diabetes by fibre source
Each group vs quintile 1Incidence rate ratio (95% CI)
Quintile 5cereal fibre
0.75(0.63–0.88)
Quintile 2fruit fibre; only Q2 showed risk reduction
0.84(0.73–0.96)
- Incident cases
- 1989
- Cereal fibre trend
- P for trend = 0.003
- Fruit fibre trend
- P for trend = 0.3
- Vegetable fibre trend
- P for trend = 0.5
Observational data: associations, not effects.
Further findings
Adjustment for body mass index (BMI) and WHR; mediation by BMI
- Proportion of fibre–diabetes relationship mediated by BMI
- 36%
- Adjustment for BMI and WHR eliminated the association
Original publication
High cereal fibre but not total fibre is associated with a lower risk of type 2 diabetes: Evidence from the Melbourne Collaborative Cohort Study. Diabetes Obes Metab. Published 3 April 2023. doi:10.
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