Hemichorea Associated With Nonketotic Hyperglycemia
Authors' conclusion
This study provides additional valuable information about the clinical and neuroimaging features of HC-NH. We hypothesize that chronic ischemia of the basal ganglia due to cerebral atherosclerosis combined with hyperglycemia is associated with HC-NH.
Study context
- Population
- Patients with hemichorea associated with nonketotic hyperglycemia (HC-NH), single center, 2000–2021; 8 men and 8 women
- Participants
- 16 patients
- Outcome
- Clinical and neuroimaging features of HC-NH
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Age, mean ± SD
- 67.6 ± 16.4 years
- Bilateral limb involvement
- 2 cases
- Hemichorea, left side
- 6
- Hemichorea, right side
- 8
- Random blood glucose at admission, average
- 17.51 ± 7.67 mmol/L
- HbA1c at admission
- 11.9%±3.1%
- History of DM
- 11 patients
- New-onset DM
- 5 patients
- Ketonuria
- 7 patients
- Typical basal ganglia hyperdensity on CT and/or hyperintensity on MRI
- 9 cases
- Chorea improved after treatment
- 15 patients
- Time to improvement of chorea
- 5.0 ± 1.9 days
Observational data: associations, not effects.
Original publication
Hemichorea Associated With Nonketotic Hyperglycemia. J Clin Endocrinol Metab. Published 17 February 2023. doi:10.
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