Health‐related quality of life of people with type 1 diabetes: An IMI2 SOPHIA post hoc analysis of FUTURE and ADJUNCT ‐ ONE
Authors' conclusion
In our population of people living with T1D, higher BMI may have adversely impacted physical domains of quality of life, but larger differences between the high- and low-quality-of-life cluster indicate that more factors play a role.
Study context
- Population
- Individuals with T1D; age 45.4 ± 15.0 years, body mass index (BMI) 26.2 ± 4.6 kg/m², diabetes duration 22.7 ± 13.5 yearspooled from two studies
- Participants
- 2,256 individuals
- Comparison
- Cluster 1 vs Cluster 2; BMI categories
- Primary endpoint
- Health-related quality of life (36-item Short-Form questionnaire), stratified by BMI and clustering
- Follow-up
- Baseline
Methodological detailsK-means clustering, referenced to 2010 US general population
- K-means clustering
- Referenced to 2010 US general population
Primary result
As reported in the abstract
SF-36 health-related quality of life
- All QoL domains slightly lower than 50 (general population mean), except vitality
- BMI ≥30 kg/m²: lower scores for bodily pain, physical functioning, general health and vitality
- Cluster differences exceeded differences between BMI categories
- Cluster 1 vs Cluster 2: P < 0.001
- Cluster 1 vs Cluster 2: P < 0.001
Original publication
Health‐related quality of life of people with type 1 diabetes: An IMI2 SOPHIA post hoc analysis of FUTURE and ADJUNCT ‐ ONE. Diabetes Obes Metab. Published 27 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →