Health-related quality of life in people with different diabetes-related foot ulcer health states: A cross-sectional study of healed, non-infected, infected, hospitalised and amputated ulcer states
Authors' conclusion
People in any DFU health state have considerably reduced HRQoL, with greatest reductions in those with infected DFU. These findings provide valuable HRQoL estimates and comparisons for several different important DFU health states, adding to our understanding of the impact of DFU on HRQoL and facilitating future economic evaluations.
Study context
- Population
- Patients attending one of 18 Diabetic Foot Services across Queensland, Australia, with one of five DFU health states; mean age 63 (12) years, 75% male
- Participants
- 376 patients
- Exposure
- Health-related quality of life (HRQoL) across five DFU health states: healed, non-infected, infected, hospitalised, amputated
- Outcome
- HRQoL measured using the EQ-5D-5L (age-sex adjusted utility values)
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Age-sex adjusted HRQoL utility (EQ-5D-5L)
Healed DFU
0.57
95% CI 0.51–0.64
Non-infected DFU
0.55
95% CI 0.49–0.62
Infected DFU
0.45
95% CI 0.36–0.55
Hospitalised DFU
0.53
95% CI 0.42–0.64
Amputated DFU
0.55
95% CI 0.46–0.63
Observational data: associations, not effects.
Original publication
Health-related quality of life in people with different diabetes-related foot ulcer health states: A cross-sectional study of healed, non-infected, infected, hospitalised and amputated ulcer states. Diabetes Res Clin Pract. Published 16 December 2023. doi:10. 1016/ j. diabres. 2023. 111061
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