Diabetes complications

Evaluation of Microvascular Complications in Kidney Recipients With Posttransplant Diabetes Mellitus

J Clin Endocrinol MetabPublished Cross-sectional study

Authors' conclusion

Cardiac autonomic neuropathy and diabetic retinopathy can affect patients with PTDM at a high rate. Diabetic retinopathy is a threat to the vision of PTDM patients. Diabetic peripheral neuropathy can be detected early in PTDM patients by CCM.

Study context

Population
Renal transplant recipients with ≥5-year history of PTDM and age-matched recipients without PTDM
Participants
41 vs 45
Exposure
Kidney recipients with PTDM vs without PTDM
  • PTDMn = 41
  • NDMn = 45reference
Outcome
Diabetic microvascular complications
Follow-up
Median 107.5 months (PTDM)
Methodological detailsage-matched controls
  • Age-matched controls

Main finding

As reported in the abstract

  • Renal functions were similar between the study groups
  • PTDM vs NDM: P = 0.02
  • PTDM vs NDM: P = 0.001
  • PTDM vs NDM: P = 0.001
  • PTDM vs NDM: P < 0.001

Observational data: associations, not effects.

Further findings

OutcomeP value
Corneal nerve fiber density by CCM, PTDM with vs without peripheral neuropathySignificantly lower with neuropathyP = 0.001

Original publication

Evaluation of Microvascular Complications in Kidney Recipients With Posttransplant Diabetes Mellitus. J Clin Endocrinol Metab. Published 15 December 2023. doi:10.1210/clinem/dgad738

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