Evaluation of Microvascular Complications in Kidney Recipients With Posttransplant Diabetes Mellitus
Authors' conclusion
Cardiac autonomic neuropathy and diabetic retinopathy can affect patients with PTDM at a high rate. Diabetic retinopathy is a threat to the vision of PTDM patients. Diabetic peripheral neuropathy can be detected early in PTDM patients by CCM.
Study context
- Population
- Renal transplant recipients with ≥5-year history of PTDM and age-matched recipients without PTDM
- Participants
- 41 vs 45
- Exposure
- Kidney recipients with PTDM vs without PTDM
- PTDMn = 41
- NDMn = 45reference
- Outcome
- Diabetic microvascular complications
- Follow-up
- Median 107.5 months (PTDM)
Methodological detailsage-matched controls
- Age-matched controls
Main finding
As reported in the abstract
- Renal functions were similar between the study groups
- PTDM vs NDM: P = 0.02
- PTDM vs NDM: P = 0.001
- PTDM vs NDM: P = 0.001
- PTDM vs NDM: P < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Corneal nerve fiber density by CCM, PTDM with vs without peripheral neuropathySignificantly lower with neuropathy | P = 0.001 |
Original publication
Evaluation of Microvascular Complications in Kidney Recipients With Posttransplant Diabetes Mellitus. J Clin Endocrinol Metab. Published 15 December 2023. doi:10. 1210/ clinem/ dgad738
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