Grocery intervention and DNA‐based assessment to improve diet quality in pediatric obesity: a pilot randomized controlled study
Authors' conclusion
Our study supports the potential of dietitian-guided food provisioning for improving diet quality in children with obesity and demonstrates an objective genomic approach for evaluating dietary shifts.
Study context
- Population
- Children with obesity aged 6–11 years
- Participants
- 33 children
- Comparison
- Food provisioning plus usual care vs usual care
- Primary endpoint
- Change in child diet quality
- Follow-up
- Week 4
Methodological detailspilot
- Pilot
Primary result
As reported in the abstract
Diet quality components
Β (whole grain increase)
0.20
95% CI 0.05–0.34P = 0.013
Intervention
Β (fiber increase)
2.52
95% CI 1.28–3.76P < 0.001
Intervention
Β (dairy decrease)
−1.31
95% CI −2.02 to −0.60P = 0.001
Intervention
Secondary outcomes
FoodSeq concordance with grocery orders
- Adjusted R2
- 0.65; p < 0.001
FoodSeq shift toward low-energy-density plant taxa, intervention vs prior survey of a related cohort
- β
- 8.64 (95% CI 5.18 to 12.14; p < 0.001)
- Comparator: prior survey of diet in related cohort (n = 195, aged 10-18 years)
Microbiome, weight and food insecurity
- No significant changes in microbiome, weight or food insecurity
Original publication
Grocery intervention and DNA‐based assessment to improve diet quality in pediatric obesity: a pilot randomized controlled study. Obesity (Silver Spring). Published 22 January 2025. doi:10.
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