Diabetes technology

Glycemic Control During the Menstrual Cycle in Women With Type 1 Diabetes: Performance of an Automated Insulin Delivery System

Diabetes Obes MetabPublished Observational cohort study

Authors' conclusion

Women with T1D using an AID system demonstrated phase-dependent differences in glycemic control, with lower time in range and greater hyperglycemia during the LLP and a higher susceptibility to hypoglycemia during the early follicular phase, accompanied by higher prandial insulin requirements.

Study context

Population
Women with T1D using the MiniMed 780G automated insulin delivery (AID) system; mean age 39.9 ± 6.3 years, diabetes duration 30.1 ± 9.7 years, BMI 25.7 ± 3.6 kg/m²48 cycles analysed
Participants
17 women
Exposure
Late luteal phase vs early follicular phase
Outcome
%TIR

Main finding

As reported in the abstract

P < 0.05

Observational data: associations, not effects.

Further findings

%TAR · higher with LLP

P < 0.01

%TBR · higher with EFP

P < 0.01

Mean glucose · higher with LLP

P < 0.01

Total daily insulin dose (TDD) · higher with LLP

P < 0.05

Prandial insulin

Basal and autocorrection doses

No significant differences in basal or autocorrection doses

Original publication

Glycemic Control During the Menstrual Cycle in Women With Type 1 Diabetes: Performance of an Automated Insulin Delivery System. Diabetes Obes Metab. Published 24 March 2026. doi:10.1111/dom.70673

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