Glucose Disorders in Patients With Pheochromocytoma/Paraganglioma: Profile and Influence Effects in a Large Cohort With 705 Patients
Authors' conclusion
Almost 70% of the patients manifested disturbances in glucose metabolism, with over one-third diagnosed with diabetes. These findings underscore the pivotal role catecholamines play in metabolic processes and emphasize the imperative need for close monitoring of blood glucose levels in patients with PPGL.
Study context
- Population
- Patients diagnosed with PPGL at Peking Union Medical College Hospital, 2018–2023
- Participants
- 705 patients
- Exposure
- Glycemic disorder vs normal glycemic
- Glycemic disordern = 492
- Normal glycemicn = 213reference
- Outcome
- Relationship between glucose metabolic disorders and catecholamine levels
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Patients diagnosed with glucose abnormalities
492 of 705
Observational data: associations, not effects.
Further findings
Metabolic characteristics
- Significantly higher HOMA-IR and TyG index, and higher HDL, LDL and total cholesterol in glycemic disorder vs normal glycemic
Original publication
Glucose Disorders in Patients With Pheochromocytoma/Paraganglioma: Profile and Influence Effects in a Large Cohort With 705 Patients. Endocr Pract. Published 16 November 2024. doi:10.
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