Adrenal Crisis and Adrenal Insufficiency Admissions in Patients 30–59 Years: Contribution of Psychosocial Factors
Authors' conclusion
These results suggest that psychosocial factors may play a role in some admissions for AI/AC in adults aged between 30 and 59 years, possibly contributing to the otherwise unexplained rise in hospitalisations for AI.
Study context
- Population
- Patients aged 30–59 years with AI hospitalised 2005–2020, regional database
- Participants
- 3,948 admissions
- Exposure
- Admissions with vs without comorbid psychosocial problems
- Outcome
- Associations between psychosocial problems and hospital admissions for AI/AC
Methodological detailsregional database, 2005–2020
- Regional database
- 2005–2020
Main finding
As reported in the abstract
Psychosocial problems in AI admissions
≥1 comorbid contributory psychological problem
25.6%
Observational data: associations, not effects.
Further findings
Trends in admissions, 2005–2020
- Admissions in women
- 63.4%
- AI admissions increase, from 61.89 to 118.44/million (p < 0.0001)
- 91.4%
- Adrenal crises (AC) admission rate increase, from 7.71 to 21.33/million (p=NS)
- 176.5%
- Secondary AI (SAI) admissions increase, from 27.98/million to 65.20/million (p < 0.001)
- 133.0%
- Admissions increased in women in each decade but only in males aged 50-59 years
Comorbid infection
- Admissions with comorbid infection
- 28.1%
Original publication
Adrenal Crisis and Adrenal Insufficiency Admissions in Patients 30–59 Years: Contribution of Psychosocial Factors. Clin Endocrinol (Oxf). Published 15 November 2024. doi:10.
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