Adrenal disease

The Cost of Adrenal Insufficiency in England—Analysis of NHS Hospital Episode Statistics (HES) Data

Clin Endocrinol (Oxf)Published Retrospective analysis of national administrative hospital data

Authors' conclusion

AI admissions have increased since 2018/19. Bed-days and cost for AC episodes have also risen. Patients with concomitant AI were more likely to have longer stays and be re-admitted. Endocrinology follow-up appears surprisingly low despite published guidelines.

Study context

Population
Hospital spells with adrenal insufficiency (AI) codes at NHS hospitals in England, financial years 2018/19 to 2022/23spells
Participants
57,125 / 12,640 / 79,965
Exposure
PAI vs AC vs UAI
  • PAIn = 57,125
  • ACn = 12,640
  • UAIn = 79,965
Outcome
Admissions, LOS and costs
Follow-up
2018/19 to 2022/23
Methodological detailsNational Hospital Episode Statistics (HES) data set, all admissions and outpatient appointments at NHS hospitals in England
  • National Hospital Episode Statistics (HES) data set
  • All admissions and outpatient appointments at NHS hospitals in England

Main finding

As reported in the abstract

Mean LOS for AC increased from 5.1 to 6.8 days

34%

Mean cost per hospital stay for AC rose since 2019/20, reaching £2959 per stay

25%

Observational data: associations, not effects.

Further findings

>1 non-elective readmission within 12 months

Patients with >1 non-elective readmission
10%

Endocrinologist follow-up · within 26 weeks of admission

Centres treating > 225 spells/year reviewed AI patients within 26 weeks
20-46%
Reviewed with a main diagnosis of AC in 2022/23
46%
Endocrinologist follow-up was lower than expected

Original publication

The Cost of Adrenal Insufficiency in England—Analysis of NHS HES Data. Clin Endocrinol (Oxf). Published 4 February 2025. doi:10.1111/cen.15207

Composed by AI from the published abstract and checked against it. How Briefs are made →

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