Obesity

Global, regional and national burden and trends of disease attributable to high body mass index in adolescents and young adults from 1990 to 2021

Diabetes Res Clin PractPublished Systematic analysis of Global Burden of Disease (GBD) 2021 data

Authors' conclusion

The burden of high BMI is still rising in AYA. Targeted measures need to be taken in different regions.

Study context

Population
Adolescents and young adults (AYA), global, regional and national, 1990–2021
Outcome
Burden of disease attributable to high BMI in AYA: age-standardized mortality and DALY rates (ASMR, ASDR) and EAPC
Follow-up
1990 to 2021
Methodological detailsage-standardized rates, estimated annual percentage change (EAPC), Pearson's correlation with sociodemographic index (SDI)
  • Age-standardized rates
  • Estimated annual percentage change (EAPC)
  • Pearson's correlation with sociodemographic index (SDI)

Main finding

As reported in the abstract

Burden attributable to high BMI in AYA

Increase in number of deaths attributable to high body mass index (BMI)

109 %

Increase in number of DALYs attributable to high BMI

141 %

Low-middle SDI regions, most significant upward trend: EAPC for ASMR

1.37

Low-middle SDI regions, most significant upward trend: EAPC for ASDR

1.97

Further findings

Correlation of ASMR and ASDR with SDI

ASMR vs SDI (negative correlation)
r = −0.13, p < 0.001
ASDR vs SDI (positive correlation)
r = 0.23, p < 0.001

Correlation with SDI of disease-specific burden due to high BMI

Osteoarthritis
r = 0.68, p < 0.001
Low back pain
r = 0.67, p < 0.001
Gout
r = 0.62, p < 0.001
These rose with SDI, contributing to the severe DALY burden in high SDI regions

Original publication

Global, regional and national burden and trends of disease attributable to high body mass index in adolescents and young adults from 1990 to 2021. Diabetes Res Clin Pract. Published 24 February 2025. doi:10.1016/j.diabres.2025.112066

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