Global, regional and national burden of ischaemic heart disease attributable to high body mass index and low physical activity from 1990 to 2021
Authors' conclusion
Since 1990, the global and regional impact of IHD attributable to high BMI and low PA remains significant, with disparities by gender, age, region and SDI. Countries should implement effective measures to control BMI and promote PA to reduce the IHD burden.
Study context
- Population
- Global, regional and national ischaemic heart disease (IHD) burden, 1990–2021, by gender, region and Socio-Demographic Index (SDI)
- Comparison
- High body mass index (BMI) vs Low physical activity (PA)
- Primary endpoint
- Deaths, DALYs and age-standardized rates for IHD attributable to high BMI and low PA
- Follow-up
- 1990 to 2021
Methodological detailsjoinpoint regression, decomposition analysis, health inequality analysis, Bayesian projection model
- Joinpoint regression
- Decomposition analysis
- Health inequality analysis
- Bayesian projection model
Primary result
As reported in the abstract
Age-standardized DALY rate, high BMI: Average annual percent change (AAPC)
−0.26
95% UI −0.45, −0.07
Age-standardized DALY rate, low PA: AAPC
−1.03
95% UI −1.18, −0.88
Age-standardized death rate, high BMI: AAPC
−0.53
95% UI −0.72, −0.33
Further findings
Distribution by gender, region and SDI
- IHD burden due to high BMI predominantly in males; low PA more prevalent in females
- Significant regional and national variation; burden shifting from high SDI to middle or low SDI regions
- Population growth and aging have exacerbated the burden
- Health inequities improved between 1990 and 2021
Projections for the next 15 years
- Rising global age-standardized DALY and death rates of IHD attributable to high BMI; those attributable to low PA may decrease
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
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