Global Incidence, Risk Factors, and Temporal Trends of Adrenal Cancer: A Systematic Analysis of Cancer Registries
Authors' conclusion
The overall incidence trend showed a decrease, with 3 countries reporting significant decreases and 1 country reporting a significant increase. Similar patterns were observed by sex and age group, except for an overall increase among the younger population.
Study context
- Population
- Global population; adrenal gland cancer (AGC) incidence in 2020, country level
- Outcome
- Global incidence (ASR) of AGC
- Follow-up
- 2020
Methodological detailsGlobal Cancer Observatory database, linear regression, Joinpoint regression
- Global Cancer Observatory database
- Linear regression
- Joinpoint regression
Main finding
As reported in the abstract
Global AGC incidence
Estimated new AGC cases globally
16 961
ASR per 100 000 persons
0.14
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| ASR by sex · 2020 | Males 0.16 · Females 0.14 |
| ASR by age · 2020 | Aged 50 to 74 years 0.31 · Aged 15 to 49 years 0.07 |
ASR by sex · 2020
- Age-standardized rates (ASRs) comparable between sexes
Risk factors for AGC incidence
- Higher AGC incidence associated with higher Human Development Index, gross domestic product, physical inactivity, obesity, hypertension and lipid disorder (β)
- 0.005-0.052
Original publication
Global Incidence, Risk Factors, and Temporal Trends of Adrenal Cancer: A Systematic Analysis of Cancer Registries. Endocr Pract. Published 10 March 2025. doi:10.
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