Global estimates of diabetes-related amputations incidence in 2010–2020: A systematic review and meta-analysis
Authors' conclusion
Globally, annual incidence of diabetes-related amputations from 2010 to 2020 has shown to disproportionately affect men and individuals with type 1 diabetes mellitus, although its incidence is not uniform across countries.
Study context
- Population
- Studies reporting incidence of diabetes-related amputations, 2010–2020 (Embase, Medline)23 studies
- Outcome
- IR of diabetes-related amputations per 100,000 individuals with diabetes
Pooled result
As reported in the abstract
IR per 100,000 individuals with diabetes
- Minor amputations, incidence rate (IR)
- 139.97 (95% CI 88.18-222.16)
- Minor amputations, T1D, IR
- 148.59 (95% CI 65.00-339.68)
- Minor amputations, T2D, IR
- 75.53 (95% CI 29.94-190.54)
- Major amputations, IR
- 94.82 (95% CI 56.62-158.80)
- Major amputations, T1D, IR
- 100.76 (95% CI 53.71-189.01)
- Major amputations, T2D, IR
- 40.58 (95% CI 11.03-149.28)
Further pooled results
Annual amputations by sex, per 100,000 with diabetes
- Women
- 83.84 (95% CI 41.67-168.65)
- Men
- 178.04 (95% CI 81.16-390.55)
Original publication
Global estimates of diabetes-related amputations incidence in 2010–2020: A systematic review and meta-analysis. Diabetes Res Clin Pract. Published 1 December 2022. doi:10.
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