Type 2 & other diabetes

Geographic variation in sodium‐glucose cotransporter 2 inhibitor and glucagon‐like peptide‐1 receptor agonist use in people with type 2 diabetes in New South Wales, Australia

Diabetes Obes MetabPublished Cross-sectional study

Authors' conclusion

The prevalence of SGLT2i and GLP-1RA use varied by geography, probably reflecting a combination of system- and prescriber-level factors. Socio-economic variation in GLP-1RA use was overshadowed by localized patterns of prescribing. Continued monitoring of variation can help shape interventions to optimize use among people who would benefit the most.

Study context

Population
New South Wales residents aged ≥40 years who dispensed metformin in 2020 (proxy for T2D)
Participants
367,829 residents
Outcome
Prevalence of SGLT2i and GLP-1 RA use among people with T2D and among people using concomitant T2D therapy, by small-level geography, age group, remoteness and socio-economic status
Follow-up
2020
Methodological detailspopulation-based, small-area geographic analysis
  • Population-based
  • Small-area geographic analysis

Main finding

As reported in the abstract

SGLT2i use, people with T2D aged 40-64
29.7%
GLP-1 RA use, people with T2D aged 40-64
8.3%
SGLT2i use among people using concomitant T2D therapy
55.4%
GLP-1 RA use among people using concomitant T2D therapy
15.4%
Localized areas of high GLP-1 RA use
2.5 times the median

Observational data: associations, not effects.

Further findings

SGLT2i and GLP-1 RA use by age group

Prevalence lower in older age groups than at 40-64 years, with similar patterns of geographic variation

Original publication

Geographic variation in sodium‐glucose cotransporter 2 inhibitor and glucagon‐like peptide‐1 receptor agonist use in people with type 2 diabetes in New South Wales, Australia. Diabetes Obes Metab. Published 15 April 2024. doi:10.1111/dom.15597

Composed by AI from the published abstract and checked against it. How Briefs are made →

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