Genetic regulation of body size and morphology in children: a twin study of 22 anthropometric traits
Authors' conclusion
Our results show high genetic correlations underlying the human body physique, suggesting that there are sets of genes widely affecting anthropometric traits. Better knowledge of these genetic variants can help to understand the development of obesity and other features of the human physique.
Study context
- Population
- Twin children aged 3–18 years, Autonomous Region of Madeira, Portugal
- Participants
- 214 twin pairs
- Outcome
- Genetic and environmental contributions to 22 anthropometric traits
Methodological detailsfactor analysis (Varimax rotation), genetic twin modeling
- Factor analysis (Varimax rotation)
- Genetic twin modeling
Main finding
As reported in the abstract
- Variation of all 22 traits explained by two factors, boys
- 80%
- Variation of all 22 traits explained by two factors, girls
- 73%
- Heritability of factors and anthropometric measures (most traits)
- 80% or more
- Genetic correlations among obesity measures
- 0.75-0.98
- Genetic correlations of height with body diameter measures (highest)
- 0.58-0.76
Original publication
Genetic regulation of body size and morphology in children: a twin study of 22 anthropometric traits. Int J Obes (Lond). Published 12 January 2023. doi:10.
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