Gender-Affirming Treatment and Employment Rate in 3812 Danish Transgender Persons and 38 120 Controls
Authors' conclusion
Masculinizing hormone treatment was associated with higher probability of employment.
Study context
- Population
- Danish persons with diagnosis code of gender dysphoria, 2000–2021; median age 19 (15; 24) years for transgender men and 23 (19; 33) years for transgender women3,812 transgender, 38,120 controls
- Participants
- 1,993 / 1,819 / 38,120
- Exposure
- Transgender persons vs cisgender controls
- Transgender menn = 1,993
- Transgender womenn = 1,819
- Cisgender controlsn = 38,120reference
- Outcome
- Employment
Methodological detailsage-matched controls (5 of same sex at birth, 5 of other sex at birth)
- Age-matched controls (5 of same sex at birth, 5 of other sex at birth)
Main finding
As reported in the abstract
Odds ratio (95% CI)
Transgender menvs Control cisgender womenbefore study inclusion
0.33(0.29–0.38)
Transgender menvs Control cisgender womenfifth calendar year after index
0.24(0.20–0.29)
Transgender womenvs Control cisgender menfifth calendar year after index
0.21(0.18–0.25)
- Between Transgender women and Control cisgender men · before study inclusion
- OR 0.30 (95% CI 0.70–0.34)
Observational data: associations, not effects.
Further findings
| Outcome | OR | P value | |
|---|---|---|---|
| Employment with gender-affirming hormone use, transgender men · all time points after 5 yearsHormone usevs No hormone useIncreased probability of employment | 1.61 (95% CI 1.08–2.42) | P = 0.02 | |
| Employment with hormone treatment, transgender women · 5 yearsHormone usevs No hormone useNot associated with changed employment rates | 1.31 (CI 0.94–1.82) | P = 0.11 | |
| 0.512Odds ratio (log scale) |
Original publication
Gender-Affirming Treatment and Employment Rate in 3812 Danish Transgender Persons and 38 120 Controls. J Clin Endocrinol Metab. Published 21 May 2024. doi:10.
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