Fractures by race and ethnicity in a diverse sample of postmenopausal women: a current evaluation among Hispanic and Asian origin groups
Authors' conclusion
In this diverse sample of postmenopausal women, we confirmed racial and ethnic differences in fracture rates and risk, with novel findings among within Asian and Hispanic subgroups.
Study context
- Population
- Postmenopausal women, Women's Health Initiative (WHI), 1998–2022
- Participants
- 160,824 women
- Exposure
- Fracture risk by race and ethnicity, and by Asian and Hispanic origin group
- Outcome
- Any clinical, hip and major osteoporotic fractures (MOFs)
- Follow-up
- Median 19.4 (IQR 9.2-24.2) years
Methodological detailsCox proportional hazards model adjusted for age and WHI clinical trial arm
- Cox proportional hazards model adjusted for age and WHI clinical trial arm
Main finding
As reported in the abstract
median 19.4 years
Any clinical fracture
44.2%
Major osteoporotic fractures (MOFs)
36 278
Hip fractures
8962
Observational data: associations, not effects.
Further findings
Any clinical fracture within Asian origin groups
- Filipina vs Japanese women: lower risk of any clinical fracture
- 24%
Fracture risk within Hispanic origin groups
- No differences in fracture risk within Hispanic origin groups
Original publication
Fractures by race and ethnicity in a diverse sample of postmenopausal women: a current evaluation among Hispanic and Asian origin groups. J Bone Miner Res. Published 15 August 2024. doi:10. 1093/ jbmr/ zjae117
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