Lipids & metabolic liver disease
Food insecurity is a risk factor for metabolic dysfunction‐associated steatotic liver disease in Latinx children
Main finding · MASLDResult — go to the resultOdds ratio 3.7 95% CI 1.5–9.0Authors' conclusion
Exposure to household food insecurity at 4 years of age was associated with increased risk for MASLD later in childhood. Further studies are needed to explore mechanism(s) and impact of reducing food insecurity on risk for MASLD.
Study context
- Population
- Latinx children of Latina mothers recruited during pregnancy, followed to early to mid-childhood
- Participants
- 136 children
- Exposure
- Household food insecurity at age 4 vs food security
- Outcome
- MASLD: Alanine transaminase (ALT) ≥95th% for age/gender plus body mass index (BMI) ≥85% at time of ALT measurement
- Follow-up
- Ages 5-12
Main finding
MASLD · early to middle childhood
Odds ratio
3.7
95% CI 1.5–9.0
P < 0.01
Food insecurevs Food secure
OR 3.7 (95% CI 1.5–9.0); P < 0.01
As reported in the abstract
Observational data: associations, not effects.
Further findings
Prevalence of household food insecurity at age 4 and MASLD
- Household food insecurity at 4 years
- 28.7%
- MASLD in early to middle childhood
- 27.2%
Food insecure among children with vs without MASLD
- Food insecure among children with MASLD
- ≈49%
- Food insecure among children without MASLD
- 21%
- With vs without MASLD
- P < 0.01
Original publication
Food insecurity is a risk factor for metabolic dysfunction‐associated steatotic liver disease in Latinx children. Pediatr Obes. Published 7 March 2024. doi:10.
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