Type 1 diabetes

Finnish children carrying the high-risk HLA genotype have a 45-fold increased risk of type 1 diabetes compared to peers with neutral or protective genotypes

Diabetes Res Clin PractPublished Cohort study

Main finding · T1D riskResult — go to the resultFold disease risk 45

Authors' conclusion

Children with the high-risk genotype have a 45-fold disease risk compared to peers with neutral or protective genotypes.

Study context

Population
Finnish children by HLA genotype risk
Exposure
High-risk HLA genotype vs neutral or protective genotypes
Outcome
Incidence rates and ratios of T1D by HLA genotype risk

Main finding

T1D risk

Fold disease risk

45

As reported in the abstract

Observational data: associations, not effects.

Original publication

Finnish children carrying the high-risk HLA genotype have a 45-fold increased risk of type 1 diabetes compared to peers with neutral or protective genotypes. Diabetes Res Clin Pract. Published 11 January 2023. doi:10.1016/j.diabres.2023.110256

Composed by AI from the published abstract and checked against it. How Briefs are made →

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