Respiratory function in uncomplicated type 1 diabetes: Blunted during exercise even though normal at rest!
Authors' conclusion
Individuals with uncomplicated type 1 diabetes display normal alveolar-capillary diffusion capacity and at rest, while their forced vital capacity, tidal volumes and VO2 are reduced during maximal exercise.
Study context
- Population
- Adults with uncomplicated T1D (HbA1c 8.0 ± 1.3%) and matched non-diabetic adults
- Participants
- 17 vs 17
- Exposure
- T1D vs matched non-diabetic adults
- T1Dn = 17
- Controln = 17reference
- Outcome
- Ventilatory response during maximal exercise and pulmonary diffusion capacity at rest
Methodological detailsmatched controls
- Matched controls
Main finding
As reported in the abstract
DLCO at rest
P = 0.2
- Tidal volume during exercise lower in T1D vs individuals without diabetes
- P < 0.05
Observational data: associations, not effects.
Further findings
Forced vital capacity at rest · lower in T1D, although in predicted normal range
P < 0.05
Forced expiratory volume 1 at rest · lower in T1D, although in predicted normal range
P < 0.05
| Outcome | T1D | Control | P value |
|---|---|---|---|
| VO2max · maximal exerciseReduced in T1D | 34.7 ± 6.8 | 37.9 ± 6.3 | P = 0.04 |
Original publication
Respiratory function in uncomplicated type 1 diabetes: Blunted during exercise even though normal at rest! Diabet Med. Published 10 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →