Gestational diabetes & diabetes in pregnancy

Fetal exposure to gestational diabetes severity and postnatal infant feeding in the first year of life associated with preadolescent obesity: a prospective cohort

Obesity (Silver Spring)Published Prospective cohort study

Authors' conclusion

BF adequacy and avoidance of sugary beverages in early life are modifiable lifestyle behaviors that may combat preadolescent obesity in infants exposed to GDM, suggesting potential longer-term benefits on child cardiometabolic health.

Study context

Population
Mother-infant dyads exposed to GDM, with monthly infant breastfeeding (BF) and sugary beverage intake reported in the first year of life and BMI measured at ages 6 to 11 years
Participants
850 mother-infant dyads
Exposure
Infant diet and GDM severity vs adequate BF without SSB/FJ
Outcome
Preadolescent overweight and obesity (BMI percentile categories)
Follow-up
Ages 6 to 11 years

Main finding

As reported in the abstract

Obesity (≥95th percentile)
Independent of GDM severity and covariates
Each group vs adequate BF, no SSB/FJAdjusted relative risk (95% CI)
Inadequate BF with SSB/FJ
1.55(1.05–2.30)
Adequate BF with SSB/FJ
1.50(1.01–2.21)

Observational data: associations, not effects.

Further findings

OutcomeaRR (95% CI)
Severe obesity (≥120% of 95th percentile) · ages 6 to 11 yearsInadequate BF with SSB/FJvs Adequate BF, no SSB/FJ3.80 (1.55–9.29)

Prevalence of BMI categories among preadolescents · ages 6 to 11 years

Overweight
17.6%
Moderate obesity
18.2%
Severe obesity
7.6%

Original publication

Fetal exposure to gestational diabetes severity and postnatal infant feeding in the first year of life associated with preadolescent obesity: a prospective cohort. Obesity (Silver Spring). Published 12 March 2025. doi:10.1002/oby.24261

Composed by AI from the published abstract and checked against it. How Briefs are made →

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