Gestational diabetes & diabetes in pregnancy
Exposure to Gestational Diabetes and Body Mass Index (BMI) Trajectories Through Adolescence: The Exploring Perinatal Outcomes Among Children Study
Authors' conclusion
Our study indicates that children who are exposed to GDM may experience higher BMI trajectories during middle childhood and adolescence, but not during early childhood. These data suggest that efforts to prevent childhood obesity among those exposed in utero to maternal GDM should start before pubertal onset.
Study context
- Population
- Mother/child dyads in the EPOCH study, Colorado; children with ≥2 longitudinal height measurements from 27 months to a maximum of 19 years
- Participants
- 403 mother/child dyads
- Exposure
- Gestational diabetes mellitus (GDM)-exposed vs not exposed offspring
- Exposedn = 76
- Not exposedn = 327reference
- Outcome
- BMI trajectories by life stage (early childhood, middle childhood, adolescence)
- Follow-up
- 27 months to 19 years
Methodological detailsgeneral linear mixed models stratified by life stage
- General linear mixed models stratified by life stage
Main finding
As reported in the abstract
BMI trajectories, GDM exposed vs not exposed, by life stage
- Exposed vs Not exposed: P = 0.27
- Exposed vs Not exposed: males: P = .005
- Exposed vs Not exposed: females: P = .002
- Exposed vs Not exposed: P = 0.02
Observational data: associations, not effects.
Original publication
Exposure to Gestational Diabetes and BMI Trajectories Through Adolescence: The Exploring Perinatal Outcomes Among Children Study. J Clin Endocrinol Metab. Published 18 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →