Obesity

Exercise modifies hypothalamic connectivity and brain functional networks in women after bariatric surgery: a randomized clinical trial

Int J Obes (Lond)Published Randomised controlled trial

Authors' conclusion

Exercise training is an important component in the management of post-bariatric patients and may improve the hypothalamic connectivity and brain functional networks that are involved in controlling food intake.

Study context

Population
Women eligible for bariatric surgery
Participants
30 women
Comparison
RYGB plus exercise training vs RYGB alone
  • RYGB + ETn = 15
  • RYGBn = 15reference

Primary result

As reported in the abstract

Brain functional connectivity

RYGB + ET vs RYGB: increased connectivity between hypothalamus and sensorial regions (seed-to-voxel analyses)

p-FDR < 0.05

RYGB + ET vs RYGB: decreased default mode network (DMN) and posterior salience (pSAL) network connectivity (ROI-to-ROI analyses)

p-FDR < 0.05

Original publication

Exercise modifies hypothalamic connectivity and brain functional networks in women after bariatric surgery: a randomized clinical trial. Int J Obes (Lond). Published 30 December 2022. doi:10.1038/s41366-022-01251-8

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