Obesity

Intermittent fasting and protein pacing are superior to caloric restriction for weight and visceral fat loss

Obesity (Silver Spring)Published Comparative intervention study

Authors' conclusion

IF-P and CR optimize weight loss, body composition, cardiometabolic health, and hunger management, with IF-P providing greater benefits.

Study context

Population
Adults with obesity
Participants
21 vs 20
Comparison
Intermittent fasting and protein pacing (IF-P) vs heart-healthy caloric restriction (CR)
  • IF-Pn = 21
  • CRn = 20reference
Outcome
Change in weight, total and visceral fat mass, desire to eat, fat-free mass percent
Methodological detailsmatched for energy intake and physical activity energy expenditure, Assessed pre- (week 0), mid- (week 5) and post- (week 9) intervention
  • Matched for energy intake and physical activity energy expenditure
  • Assessed pre- (week 0), mid- (week 5) and post- (week 9) intervention

Main finding

As reported in the abstract

Weight change, IF-P vs CR
−9% vs. −5%
Total fat mass change, IF-P vs CR
−16% vs. −9%
Visceral fat mass change, IF-P vs CR
−33% vs. −14%
Desire to eat change, IF-P vs CR
−17% vs. 1%
Fat-free mass percent increase, IF-P vs CR
6% vs. 3%

Further findings

Weekly total energy intake

P = 0.90

Physical activity energy expenditure

P = 0.79

Within-group changes

Both groups reduced weight, total and visceral fat mass, BP, lipids and desire to eat, and increased fat-free mass proportion (p < 0.05)

Original publication

Intermittent fasting and protein pacing are superior to caloric restriction for weight and visceral fat loss. Obesity (Silver Spring). Published 27 December 2022. doi:10.1002/oby.23660

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