Excellence in the management of Advanced Hybrid Closed-Loop Systems: Lessons from the Polish cohort
Authors' conclusion
The Polish MM780G users achieved better glycemic control than the general European population (excluding Poland). This is largely attributable to the adoption of optimal settings in Poland and the already high glycemic outcomes at system start. As these characteristics can be implemented elsewhere, we believe this outstanding result can be obtained in other countries as well.
Study context
- Population
- MiniMed 780G Advanced Hybrid Closed Loop (AHCL) system users who uploaded CareLink Personal data, August 2020 to December 2022
- Participants
- 1,304 vs 55,659
- Exposure
- MM780G users in Poland vs European region excluding Poland
- Poland (PL)n = 1,304
- Excluding Poland (EU-PL)n = 55,659reference
- Outcome
- TIR
Methodological detailsCareLink Personal data
- CareLink Personal data
Main finding
As reported in the abstract
Observational data: associations, not effects.
Further findings
TBR<54 mg/dL
TBR<70 mg/dL
Adoption of optimal settings (GT=100 mg/dL, AIT=2hr)
- Univariable analysis of post-AHCL Time in Range (TIR)
- P = 0.15
- Univariable analysis of post-AHCL TIR: geography not a significant contributor to high post-AHCL TIR
Adoption of optimal settings (GT=100 mg/dL, AIT=2hr)
- Filtering on optimal-setting users led to less pronounced differences in glycemic control between PL and EU-PL
Univariable analysis of post-AHCL TIR
- Much of the Polish post-AHCL TIR explained by high pre-AHCL TIR
Original publication
Excellence in the management of Advanced Hybrid Closed-Loop Systems: Lessons from the Polish cohort. Diabetes Res Clin Pract. Published 22 August 2024. doi:10.
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