Evaluation of Stress Response in Middle-Aged Male Diabetic Hypertensive Patients
Authors' conclusion
The arithmetic problem-solving task used with the HT&DM and HT patients was useful as an acute stress test in the laboratory environment. There was no statistically significant difference for group × time interaction factor between the HT&DM and HT groups; however, the salivary cortisol and BP values increased significantly after acute stress within each group.
Study context
- Population
- Patients with Hypertension (HT)&DM and HT treated in the outpatient clinic of the Medical Pharmacology and Clinical Pharmacology Department, Istanbul University, Istanbul Medical Faculty Hospital
- Participants
- 62 patients
- Comparison
- HT&DM vs HT: response to acute cognitive stress
- Outcome
- Salivary cortisol changes in the cognitive stress response
Methodological detailsacute laboratory stress test (arithmetic task), repeated-measures ANOVA
- Acute laboratory stress test (arithmetic task)
- Repeated-measures ANOVA
Main finding
As reported in the abstract
Salivary cortisol level (repeated ANOVA)
Main effect of time: F (1.842, 60)
8.771
P < .0001
Further findings
| Outcome | P value |
|---|---|
| SBP and DBP values between groupsBetween HT&DM and HT · SBP; no statistically significant difference | P = 0.331 |
| SBP and DBP values between groupsBetween HT&DM and HT · DBP; no statistically significant difference | P = 0.058 |
- Systolic blood pressure (SBP) (repeated ANOVA) — Main effect of time: F (2.185, 60) · not significant
- 12.080, P < .0001 · P = 0.751
- Diastolic blood pressure (DBP) (repeated ANOVA) — Main effect of time: F (2.793, 60) · not significant
- 6.043, P = .001 · P = 0.713
- Heart rate (repeated ANOVA) — Main effect of time: F (2.073, 60) · not significant
- 13.259, P < .0001 · P = 0.506
Original publication
Evaluation of Stress Response in Middle-Aged Male Diabetic Hypertensive Patients. J Clin Endocrinol Metab. Published 6 March 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →