Evaluation of aggression level in adolescent girls with classical congenital adrenal hyperplasia
Authors' conclusion
In this study, we found no difference between the aggression scores of adolescents with classical CAH compared to their healthy peers. The total aggression score and subscale were similar in unaffected female adolescents.
Study context
- Population
- Adolescents aged 13–20 years with classical congenital adrenal hyperplasia (CAH) due to 21 hydroxylase or 11β hydroxylase deficiency, and healthy controls of the same age group
- Participants
- 20 / 20 / 20 / 20
- Exposure
- Adolescents with classical CAH vs healthy peers
- Girls with CAHn = 20
- Healthy girlsn = 20reference
- Boys with CAHn = 20
- Healthy boysn = 20reference
- Outcome
- Aggression level: total Buss-Perry Aggression Scale (BPAS) score (physical aggression, verbal aggression, hostility, angry behaviors)
Main finding
As reported in the abstract
Total aggression scale score (BPAS)
Girls with CAH
73.3
± 14.6
Healthy girls
74.1
± 11.2
Boys with CAH
71.5
± 14.8
Healthy boys
75.3
± 14.5
P > 0.05
Observational data: associations, not effects.
Further findings
Buss-Perry Aggression Scale (BPAS) subscale scores (physical aggression, verbal aggression, hostility, anger)
- No difference between the subscale scores of patients and healthy adolescents
Aggression scores by age in adolescents with CAH
- Aggression scores in adolescents with CAH increased significantly with age
Original publication
Evaluation of aggression level in adolescent girls with classical congenital adrenal hyperplasia. Clin Endocrinol (Oxf). Published 26 June 2023. doi:10.
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