Reproductive endocrinology

Ethnicity and the Prevalence of Polycystic Ovary Syndrome: The Eastern Siberia PCOS Epidemiology and Phenotype Study

J Clin Endocrinol MetabPublished Cross-sectional study

An erratum to this article was published (J Clin Endocrinol Metab, 18 Dec 2024 ↗)

Authors' conclusion

We observed a 15.1% prevalence of PCOS in our medically unbiased population of premenopausal women. In this population of Siberian premenopausal women of Caucasian, Asian, and mixed ethnicity living in similar geographic and socioeconomic conditions, the prevalence was higher in Caucasian or mixed than Asian women. These data highlight the need to assess carefully ethnic-dependent differences in the frequency and clinical manifestation of PCOS.

Study context

Population
Unselected multiethnic premenopausal women undergoing mandatory annual employment-related health assessment at main regional employers, Irkutsk Region and Buryat Republic, Russia, 2016–20191,134 complete evaluation
Participants
1,398 women
Exposure
PCOS prevalence by ethnicity: Caucasian and mixed vs Asian
Outcome
PCOS prevalence, overall and by ethnicity
Methodological detailsmulticenter, prospective
  • Multicenter
  • Prospective

Main finding

As reported in the abstract

PCOS prevalence

Pz < .05

Total prevalence of PCOS in the population
15.1%
PCOS diagnosed among women with complete evaluation
165/1134 (14.5%)

Observational data: associations, not effects.

Further findings

Estimated weight-adjusted PCOS prevalence in women with incomplete evaluation

Estimated weight-adjusted prevalence in 264 women with incomplete evaluation
46.2 or 17.5%

Original publication

Ethnicity and the Prevalence of Polycystic Ovary Syndrome: The Eastern Siberia PCOS Epidemiology and Phenotype Study. J Clin Endocrinol Metab. Published 18 June 2024. doi:10.1210/clinem/dgae424

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