Epidemiology and Management of Moderate to Severe Thyroid Eye Disease in the United States: Analysis of a Healthcare Claims Database
Authors' conclusion
The estimated incidence and prevalence rates of TED demonstrate the considerable impact of this disease in the United States, making the creation of a specific ICD code imperative for effective healthcare planning and management.
Study context
- Population
- Patients with moderate to severe thyroid eye disease (TED) in the United States, Inovalon deidentified claims database (claims through 2019)
- Exposure
- Sensitive definition vs Specific definition
- Outcome
- Incidence and prevalence of moderate to severe TED
Methodological detailshealthcare claims database, sensitive and specific case definitions
- Healthcare claims database
- Sensitive and specific case definitions
Main finding
As reported in the abstract
Adjusted incidence rate (age- and gender-adjusted), per 100,000 person-years
| Group | Value | Women | Men |
|---|---|---|---|
| Sensitive definition | 8.97 per 100,000 person-years | 13.49 | 4.27 |
| Specific definition | 4.37 per 100,000 person-years | 6.59 | 2.05 |
Value
Sensitive definition8.97 per 100,000 person-years
Specific definition4.37 per 100,000 person-years
Women
Sensitive definition13.49
Specific definition6.59
Men
Sensitive definition4.27
Specific definition2.05
Observational data: associations, not effects.
Further findings
Adjusted prevalence rate, per 100,000 persons
Women Sensitive definition 66.00 · Specific definition 31.18
Men Sensitive definition 21.39 · Specific definition 9.50
Patient characteristics and management
- Prevalent patients with hypertension
- > 40%
- Preponderance of women
- Steroids were the most frequently prescribed medication
- Impact of teprotumumab not captured (claims only through 2019)
Original publication
Epidemiology and Management of Moderate to Severe Thyroid Eye Disease in the United States: Analysis of a Healthcare Claims Database. Clin Endocrinol (Oxf). Published 17 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →