Endocrine Care During Transition in Emerging Adults With Cystic Fibrosis: A Single Center Retrospective Study
Authors' conclusion
Health outcome measures of CFRD and CFBD worsen during transition from pediatric to adult CF care at a single CF Care Center. Physicians should recognize this vulnerable period of transition and institute programs to increase screening of CFRD and CFBD during this period.
Study context
- Population
- Emerging adults aged 18–30 with cystic fibrosis (CF) who transitioned to a single-centre adult CF clinic, January 2013–June 2023
- Participants
- 94 adults
- Outcome
- Changes in glycemic control in participants with CFRD and bone density in all participants
- Follow-up
- Up to 10 years after transition to adult CF care
Methodological detailssingle-centre, retrospective chart review
- Single-centre
- Retrospective chart review
Main finding
As reported in the abstract
HbA1c in participants with cystic fibrosis-related diabetes (CFRD) on insulin, geometric mean, increased from
7.8%
62 mmol/mol
HbA1c in participants with CFRD on insulin, geometric mean, after 5 years of adult follow up
9.4%
79 mmol/molP = .003
All emerging adults with at least one BMD Z-score < −1
47%
Observational data: associations, not effects.
Further findings
- Completion rates of OGTT and DXA screenings were low
Original publication
Endocrine Care During Transition in Emerging Adults With Cystic Fibrosis: A Single Center Retrospective Study. Endocr Pract. Published 12 February 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →