Efficacy of intermittent short‐term use of a real‐time continuous glucose monitoring system in non‐insulin–treated patients with type 2 diabetes: A randomized controlled trial
Primary result · Change in HbA1cResult — go to the resultAdjusted difference −0.68 %Authors' conclusion
In non-insulin-treated patients with T2D uncontrolled with OADs, intermittent short-term use of RT-CGM was an effective method for glucose control, especially in those performing SMBG frequently.
Study context
- Population
- Non-insulin-treated patients with T2D uncontrolled with oral antidiabetic drugs (OADs); baseline HbA1c 8.2% ± 0.5%48 completed
- Participants
- 61 patients
- Comparison
- Intermittent short-term real-time continuous glucose monitoring (RT-CGM) vs control
- Primary endpoint
- Change in HbA1c
- Follow-up
- 6 months
Methodological detailsmulticentre, prospective, All participants used blinded CGM for up to 6 days with education before randomization; RT-CGM additionally applied for 1 week in intervention groups
- Multicentre
- Prospective
- All participants used blinded CGM for up to 6 days with education before randomization; RT-CGM additionally applied for 1 week in intervention groups
Primary result
As reported in the abstract
Adjusted difference
−0.68 %
P = 0.018
Further findings
| Outcome | Adjusted difference (%) | P value |
|---|---|---|
| Change in HbA1c · 3 monthsTreatment group 1 vs Control | −0.60 | P = 0.044 |
| Change in HbA1c · 3 monthsTreatment group 2 vs Control | −0.64 | P = 0.014 |
HbA1c change by self-monitoring of blood glucose (SMBG) frequency (treatment groups) · 3 and 6 months
- SMBG ≥1.5 times/day: significant HbA1c improvement at 3 and 6 months
- SMBG <1.5 times/day: no significant improvement
Original publication
Efficacy of intermittent short‐term use of a real‐time continuous glucose monitoring system in non‐insulin–treated patients with type 2 diabetes: A randomized controlled trial. Diabetes Obes Metab. Published 23 September 2022. doi:10.
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