Impact of pre- and post-exercise strategies on hypoglycemic risk for two modalities of aerobic exercise among adults and adolescents living with type 1 diabetes using continuous subcutaneous insulin infusion: A randomized controlled trial
Authors' conclusion
Compared to INT, CONT led to greater blood glucose decline without increasing hypoglycemia risk. A larger pre-exercise BRR did not further reduce hypoglycemia risk during exercise. Post-exercise INS and snack strategies led to comparable glucose profiles in pwT1D.
Study context
- Population
- Adults and adolescents with T1D using CSII; HbA1c 7.5 ± 1.0 %; post-absorptive (4-h post-meal) sessions21 adults · 16 adolescents
- Participants
- 37 participants
- Comparison
- CONT vs INT exercise; 40% vs 80% pre-exercise basal rate reduction (BRR); post-exercise INS vs snack
Methodological detailscrossover
- Crossover
Primary result
As reported in the abstract
during exercise
| Group | Value | Hypoglycemic events |
|---|---|---|
| CONT | −3.1 ± 2.3 mmol/l | 31 |
| INT | −2.7 ± 2.2 mmol/l | 28 |
Value
CONT−3.1 ± 2.3 mmol/l
INT−2.7 ± 2.2 mmol/l
Hypoglycemic events
CONT31
INT28
- CONT vs INT: P = 0.005 — greater blood glucose decrease with CONT
Further findings
| Outcome | 40 %BRR | 80 %BRR | P value |
|---|---|---|---|
| Blood glucose change and hypoglycemic events during exercise, 40% vs 80% BRRSimilar | −3.0 ± 2.4 mmol/l | −2.8 ± 2.1 mmol/l | P = 0.076 |
| Hypoglycemic events | 35 | 24 |
Time in hyperglycemia after exercise, INS vs snack
- Lower with INS vs snack in first 30 min after exercise
- No differences for late recovery period or nighttime
Original publication
Impact of pre- and post-exercise strategies on hypoglycemic risk for two modalities of aerobic exercise among adults and adolescents living with type 1 diabetes using continuous subcutaneous insulin infusion: A randomized controlled trial. Diabetes Metab. Published 7 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →