Effects of hypoxic training interventions on cardiometabolic health of adults with overweight and obesity: A systematic review and meta‐analysis
An erratum to this article was published (Diabetes Obes Metab, Oct 2026 ↗)
Authors' conclusion
Hypoxic training did not outperform normoxic training in improving cardiometabolic outcomes.
Study context
- Population
- Adults with overweight or obesity; RCTs from PubMed, Web of Science and Cochrane Library (up to June 2025)
- Participants
- 278 adults9 RCTs
- Comparison
- Hypoxic vs normoxic training
- Outcome
- Fasting glucose and fasting insulin
Methodological detailssubgroup, moderation and sensitivity analyses
- Subgroup, moderation and sensitivity analyses
Pooled result
As reported in the abstract
Heterogeneity (I2)
60%-77%
Further pooled results
| Outcome | P value |
|---|---|
| Lipid profile markers and blood pressureNo significant between-group differences · moderate to high heterogeneity | all p > 0.05 |
Subgroup and moderation analyses
- Greater fasting glucose reductions suggested with shorter and lower-intensity hypoxic interventions
Original publication
Effects of hypoxic training interventions on cardiometabolic health of adults with overweight and obesity: A systematic review and meta‐analysis. Diabetes Obes Metab. Published 18 November 2025. doi:10. 1111/ dom. 70303
Composed by AI from the published abstract and checked against it. How Briefs are made →