Diabetes technology

Effects of Continuous Glucose Monitoring Discontinuation in Adults With Type 2 Diabetes Not Using Insulin

J Diabetes Sci TechnolPublished Follow-up study of the UNITE study

Authors' conclusion

In noninsulin-using people with T2D, glycemic measures improved with real-time CGM use, but these improvements deteriorated substantially and significantly when CGM use was discontinued. More research and more sensitive behavioral assessments are needed to better understand which factors and behavior changes may account for the glycemic decline.

Study context

Population
Noninsulin-using adults with T2D
Comparison
Continuous glucose monitoring (CGM) discontinuation vs Phase 1 Post-intervention period
Outcome
Percent TIR 70 to 180 mg/dL
Follow-up
After 4 months of CGM discontinuation
Methodological detailsblinded CGM, before-after comparison
  • Blinded CGM
  • Before-after comparison

Main finding

As reported in the abstract

95% CI −22% to −12%; P < 0.0001

Further findings

Additional glycemic metrics

Several additional glycemic metrics worsened significantly from Post to Follow-up
P < 0.05

Dietary intake and exercise

Not statistically different at Follow-up vs Post
P > 0.05

Physical activity

Physical activity decreased at Follow-up vs Post
P = 0.01

Original publication

Effects of Continuous Glucose Monitoring Discontinuation in Adults With Type 2 Diabetes Not Using Insulin. J Diabetes Sci Technol. Published 29 December 2025. doi:10.1177/19322968251404496

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