Effects of concurrent aerobic and strength training in patients with type 2 diabetes: Bayesian pairwise and dose-response meta-analysis
Pooled result · HbA1cResult — go to the resultMD −0.48 % 95% CrI −0.55 to −0.40Authors' conclusion
CT significantly improves several health indicators in patients with type 2 diabetes. A non-linear dose-response relationship was observed between the training dose of CT and HbA1c
Study context
- Population
- Patients with T2D; 52/48 male/female ratio; mean age range 50–65 years
- Participants
- 1,948 patients23 randomized controlled trials (RCTs)
- Comparison
- Concurrent aerobic and strength training vs control
- Outcome
- HbA1c
Methodological detailsBayesian hierarchical random-effects modeling, pairwise and dose-response meta-analysis, Search of PubMed, Embase, Web of Science and Cochrane Library to March 2024, Risk of bias assessed by two independent authors with Cochrane tools
- Bayesian hierarchical random-effects modeling
- Pairwise and dose-response meta-analysis
- Search of PubMed, Embase, Web of Science and Cochrane Library to March 2024
- Risk of bias assessed by two independent authors with Cochrane tools
Pooled result
As reported in the abstract
MD
−0.48 %
95% CrI −0.55 to −0.40
Concurrent aerobic and strength training (CT)vs control
MD −0.48 % (95% CrI −0.55 to −0.40)
- Heterogeneity among different levels (SD)
- 0.31 (95% CrI: 0.17 to 0.51)
Further pooled results
Fasting blood glucose (FBG)
| MD (mmol/L) (95% CrI) | ||
|---|---|---|
| CTCrI | −0.48 (−0.55 to −0.40) | |
| −1−0.500.5Difference, mmol/L (linear scale) |
Dose-response of CT and HbA1c
| MD (%) (95% CrI) | ||
|---|---|---|
| CT at optimal dose 1030 METs-min/weekCrI; SE=0.11 | −0.47 (−0.68 to −0.26) | |
| −1−0.500.5Difference, % (linear scale) |
- FBG — Greater heterogeneity (SD)
- 17.73 (95% CrI: 11.23 to 28.09)
- Dose-response of CT and HbA1c — Non-linear dose-response relationship; optimal dose (METs-min/week)
- 1030
- FBG: 95% CrI
- Dose-response of CT and HbA1c: 95% CrI
Original publication
Effects of concurrent aerobic and strength training in patients with type 2 diabetes: Bayesian pairwise and dose-response meta-analysis. BMJ Open Diabetes Res Care. Published 28 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →