Effects of Attention-deficit/hyperactivity disorder (ADHD) and ADHD treatment on glycemic management in type 1 diabetes: A systematic review and meta-analysis of observational studies
Pooled result · Mean HbA1cResult — go to the resultMD 0.60 95 % CI 0.41–0.79Authors' conclusion
ADHD is associated with higher HbA1c and increased acute diabetes-related complications. More research is needed to assess the effects of ADHD treatments on T1D management.
Study context
- Population
- Individuals with T1D; literature search of PubMed, EMBASE, CINAHL, Scopus, PsycINFO, CENTRAL and Web of Science up to November 22, 202317 studies
- Comparison
- T1D with ADHD vs without ADHD; ADHD treatment vs no treatment
- Outcome
- HbA1c and acute complications
Pooled result
Mean HbA1c
MD
0.60
95 % CI 0.41–0.79
P < 0.001
ADHDvs Without ADHD
MD 0.60 (95 % CI 0.41–0.79); P < 0.001
As reported in the abstract
Further pooled results
| Outcome | Mean difference (95 % CI) | P value | |
|---|---|---|---|
| Mean HbA1c by ADHD treatmentADHD treatmentvs No ADHD treatmentI2 = 78.6 %; no difference | −0.52 (−1.16 to 0.13) | P = 0.12 | |
| −1.5−1−0.500.5Difference (linear scale) |
Suboptimal HbA1c, hospitalization, DKA and hypoglycemia
- Rates all substantially higher in T1D with ADHD than without ADHD
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Effects of ADHD and ADHD treatment on glycemic management in type 1 diabetes: A systematic review and meta-analysis of observational studies. Diabetes Res Clin Pract. Published 13 February 2024. doi:10.
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