Obesity

Effectiveness of Telemedicine Prescribing and a Long‐Acting Obesity Medication Behavioral Program: A 24‐Week Single‐Arm Study

Obesity (Silver Spring)Published Single-arm study

Authors' conclusion

Virtually delivered treatment combining telemedicine and a behavioral program tailored for long-acting AOMs demonstrated clinically significant improvements in weight, BP, diet, and activity over 24 weeks.

Study context

Population
Participants from a telehealth medical obesity program; mean age 44.1, 91% female, 81% White, mean weight 102.8 kg
Participants
180 participants
Outcome
Weight loss
Follow-up
24 weeks
Methodological detailstelehealth, virtual behavioral program
  • Telehealth
  • Virtual behavioral program

Main finding

As reported in the abstract

Weight loss at 24 weeks (SD 6.9%; p < 0.0001)

12.3%

Further findings

Weight loss · 12 weeks

Weight loss at 12 weeks (SD 5.2%)
7.2%

Mean blood pressure (BP) · baseline, 12 and 24 weeks

Mean BP at baseline (SD 17.2/12.2)
131.0/83.8
Mean BP at 12 weeks (SD 13.7/10.1)
122.5/78.7
Mean BP at 24 weeks (SD 13.5/10.6; p < 0.0001)
120.0/78.2

Eating habits, diet quality and activity

Participants significantly improved their eating habits, diet quality, and activity

Safety

Side effects were markedly lower than in previously reported trials

Original publication

Effectiveness of Telemedicine Prescribing and a Long‐Acting Obesity Medication Behavioral Program: A 24‐Week Single‐Arm Study. Obesity (Silver Spring). Published 18 November 2025. doi:10.1002/oby.70056

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