Obesity

Twenty‐Four Month Outcomes From a Real‐World Telehealth Obesity Treatment Clinic Using Obesity Medications

Obesity (Silver Spring)Published Retrospective observational study

Authors' conclusion

This real-world analysis found 18- and 24-month weight losses comparable to those demonstrated in clinical trials, supporting the long-term efficacy of AOMs provided by a telemedicine weight management clinic. Continued weight loss was demonstrated between 18 and 24 months, suggesting sustained engagement with AOMs and a telemedicine weight management clinic support continued weight loss in the long term.

Study context

Population
Adults using antiobesity medications (AOMs) at a telemedicine weight management clinic, January 2022–December 2024
Participants
11,675 vs 4,317
Exposure
≥ 18 months vs ≥ 24 months
  • ≥ 18 monthsn = 11,675
  • ≥ 24 monthsn = 4,317
Outcome
Total body weight change across all AOMs
Follow-up
18 and 24 months
Methodological detailsreal-world, telemedicine weight management clinic
  • Real-world
  • Telemedicine weight management clinic

Main finding

As reported in the abstract

Average total body weight reduction, all AOMs

≥ 18 months

−18.53%

average · CI −18.74%–-18.32%

≥ 24 months

−20.27%

average · CI −20.63%–-19.92%

Observational data: associations, not effects.

Further findings

Weight loss by AOM class

Outcomes trended toward greater weight loss with long-acting AOMs vs oral AOMs

Original publication

Twenty‐Four Month Outcomes From a Real‐World Telehealth Obesity Treatment Clinic Using Obesity Medications. Obesity (Silver Spring). Published 1 March 2026. doi:10.1002/oby.70156

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