Effect of Testosterone on Asthma Exacerbations
Authors' conclusion
Our study shows that TTh or ADT in men with asthma is not associated with a change in asthma exacerbations.
Study context
- Population
- Adult men with asthma who received testosterone therapy (TTh) or androgen deprivation therapy (ADT), tertiary hospital EHR database
- Participants
- 229 / 229 / 93 / 93
- Exposure
- Asthma exacerbation rate before vs during TTh or ADT
- Before TThn = 229reference
- On TThn = 229
- Before ADTn = 93reference
- During ADTn = 93
- Outcome
- Rate of asthma exacerbations per 1,000 patient-years (hospitalization due to asthma or oral prednisone in outpatient setting)
Methodological detailssingle-centre, electronic health records, before–during comparison
- Single-centre
- Electronic health records
- Before–during comparison
Main finding
As reported in the abstract
Asthma exacerbations per 1,000 patient-years
Before TTh vs On TTh
- Rate ratio
- rate ratio 1.1 (95% CI 0.0–1.5); P = 0.70
Before ADT vs During ADT
- Rate ratio
- rate ratio 1.0 (95% CI 0.0, undefined); P = 0.50
Observational data: associations, not effects.
Further findings
Duration of TTh
- Median duration of TTh (IQR 2.4, 9.1)
- 5.3 years
Duration of ADT
- Median duration of ADT (IQR 1.0, 4.0)
- 2.05 years
Original publication
Effect of Testosterone on Asthma Exacerbations. Endocr Pract. Published 22 July 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →