Effect of SARS-CoV-2 Infection on Incident Diabetes by Viral Variant: Findings From the National COVID Cohort Collaborative (N3C)
Authors' conclusion
Incident diabetes risk after COVID-19 was similar across different SARS-CoV-2 variants. However, there was greater latency in diabetes onset in the Omicron variant era.
Study context
- Population
- Adults in National COVID Cohort Collaborative (N3C) data
- Exposure
- COVID-positive adults vs COVID-negative controls or controls with acute respiratory illness (ARI), by viral variant era
- Outcome
- Cumulative incidence ratio (CIR) of incident diabetes for each viral variant era
- Follow-up
- 1 year
Methodological detailsweighted on demographics, data site and Charlson comorbidity index score
- Weighted on demographics, data site and Charlson comorbidity index score
Main finding
As reported in the abstract
Incident diabetes, CIR by variant era · 1 year after COVID-19
Cumulative incidence ratio (CIR)
- COVID-positive (ancestral) vs COVID-negative
- 1.16 (95% CI 1.12–1.21)
- COVID-positive (Alpha) vs COVID-negative
- 1.14 (95% CI 1.11–1.17)
- COVID-positive (Delta) vs COVID-negative
- 1.17 (95% CI 1.13–1.21)
- COVID-positive (Omicron) vs COVID-negative
- 1.13 (95% CI 1.10–1.17)
- COVID-positive (ancestral) vs ARI
- 1.17 (95% CI 1.11–1.22)
- COVID-positive (Alpha) vs ARI
- 1.14 (95% CI 1.09–1.19)
- COVID-positive (Delta) vs ARI
- 1.18 (95% CI 1.11–1.26)
- COVID-positive (Omicron) vs ARI
- 1.20 (95% CI 1.13–1.27)
Observational data: associations, not effects.
Further findings
Timing of incident diabetes risk
- Latency with Omicron: unlike other variants, risk presented after 180 days
Original publication
Effect of SARS-CoV-2 Infection on Incident Diabetes by Viral Variant: Findings From the National COVID Cohort Collaborative (N3C). Diabetes Care. Published 29 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →