Gestational diabetes & diabetes in pregnancy
Effect of artificial pancreas system use on glycaemic control among pregnant women with type 1 diabetes mellitus: A meta‐analysis of randomized controlled trials
Pooled result · 24-hour TIRResult — go to the resultSMD 0.53 95% CI 0.25–0.80Authors' conclusion
Our findings suggest that APS might improve 24-hour TIR and overnight glycaemic control, and 24-hour APS use also significantly reduced 24-hour TBR (2.8 mmol/L) among pregnant women with T1DM.
Study context
- Population
- Pregnant women with T1D; 5 databases searched before October 9, 2023
- Participants
- 164 women4 RCTs
- Comparison
- Artificial pancreas systems vs standard care
- Outcome
- 24-hour time in range (TIR) (3.5-7.8 mmol/L)
Pooled result
24-hour TIR
SMD
0.53
95% CI 0.25–0.80
P < 0.001
APSvs Standard care
SMD 0.53 (95% CI 0.25–0.80); P < 0.001
As reported in the abstract
Further pooled results
| Outcome | SMD (95% CI) | P value | |
|---|---|---|---|
| Overnight TIR | 0.67 (0.39–0.95) | P < 0.001 | |
| Overnight TBR (<3.5 mmol/L) | −0.49 (−0.77 to −0.21) | P < 0.001 | |
| 24-hour TIR, subgroup of 24-hour APS use (overnight trial removed)Subgroup analysis | 0.41 (0.12–0.71) | P = 0.007 | |
| 24-hour TBR (<2.8 mmol/L), subgroup of 24-hour APS use (overnight trial removed)Subgroup analysis | −0.77 (−1.32 to −0.23) | P = 0.006 | |
| −2−101Difference (linear scale) |
24-hour TAR, 24-hour TBR and MBG
- No significant difference between the two groups
Original publication
Effect of artificial pancreas system use on glycaemic control among pregnant women with type 1 diabetes mellitus: A meta‐analysis of randomized controlled trials. Diabetes Obes Metab. Published 12 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →