Early identification of postoperative remission for thyrotropin‐secreting adenomas
Authors' conclusion
Tumour size and extent are major prognostic factors for remission. Postoperative thyroid function at 3 months could be used as a clinical prediction tool for long-term endocrinological remission.
Study context
- Population
- Patients diagnosed with TSH-secreting adenoma (TSHoma) and surgically treated at a single hospital, January 2015 to June 2021
- Participants
- 63 patients
- Exposure
- Remission vs nonremission after surgery
- Outcome
- Long-term postoperative endocrinological remission and its predictors (preoperative characteristics, postoperative thyroid function)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Postoperative endocrinological remission
Achieved postoperative endocrinological remission
88.14%
Postoperative thyroid function at 3 months was a viable diagnostic predictor for remission, especially FT4 with cutoff
20.65 pmol/L
Observational data: associations, not effects.
Further findings
Demographic and clinical characteristics · diagnosis
- Male to female ratio
- 1.25
- Mean age at diagnosis
- 45 ± 12 years
- Hyperthyroidism
- 68.25%
- Space-occupying effect
- 15.87%
- Amenorrhea (of female patients)
- 7.14%
- No symptoms
- 22.22%
Original publication
Early identification of postoperative remission for thyrotropin‐secreting adenomas. Clin Endocrinol (Oxf). Published 31 May 2024. doi:10.
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