Dynamics of Apolipoprotein J Levels and Metabolic Parameters Following Bariatric Surgery
Authors' conclusion
These findings suggest that although overall ApoJ levels did not change significantly, individual temporal variations were associated with changes in leptin levels, indicating that ApoJ may serve as a potential biomarker after RYGB.
Study context
- Population
- Obese patients undergoing RYGB surgery
- Participants
- 7 patients
- Outcome
- Serial changes in ApoJ levels and their associations with responses of adiponectin levels and metabolic parameters
- Follow-up
- From 1 day up to 12 months post-surgery
Main finding
As reported in the abstract
ApoJ levels after RYGB · up to 12 months
Positive association of Apolipoprotein J (ApoJ) changes with changes in leptin levels
r² = 0.499
p = 0.024
Observational data: associations, not effects.
Further findings
Anthropometric and metabolic parameters · post-surgery
- Marked improvements in anthropometric measures and serum glucose, insulin, leptin, GLP-1, adiponectin, homeostatic model assessment of insulin resistance (HOMA-IR) and HOMA-ß
Original publication
Dynamics of Apolipoprotein J Levels and Metabolic Parameters Following Bariatric Surgery. Clin Endocrinol (Oxf). Published 21 December 2025. doi:10. 1111/ cen. 70087
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