The efficacy of GLP‐1RAs for the management of postprandial hypoglycemia following bariatric surgery: a systematic review
Authors' conclusion
This first, to the authors' knowledge, systematic review presents evidence suggesting that use of GLP-1RAs does not lead to an increase of hypoglycemic episodes, and, although this approach may appear counterintuitive, the findings suggest that GLP-1RAs could reduce the number of postprandial hypoglycemic episodes and improve glycemic variability.
Study context
- Population
- Patients with postprandial hyperinsulinemic hypoglycemia following RYGB or gastric sleeve surgery
- Comparison
- GLP-1 RA for postprandial hypoglycaemia after bariatric surgery
- Outcome
- Hypoglycemic episodes and glycemic variability
Methodological detailsPRISMA-P, Cochrane Handbook methods
- PRISMA-P
- Cochrane Handbook methods
Pooled result
As reported in the abstract
- GLP-1RA use does not lead to an increase of hypoglycemic episodes
- GLP-1RAs could reduce the number of postprandial hypoglycemic episodes and improve glycemic variability
Original publication
The efficacy of GLP‐1RAs for the management of postprandial hypoglycemia following bariatric surgery: a systematic review. Obesity (Silver Spring). Published 10 December 2022. doi:10.
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