Dynamic fronto‐amygdalar interactions underlying emotion‐regulation deficits in women at higher weight
Authors' conclusion
These findings support a framework involving alterations in fronto-amygdalar connectivity contributing to difficulties in regulating negative affect in individuals at higher weight.
Study context
- Population
- Adult women with obesity and control participants
- Participants
- 48 vs 54
- Comparison
- Women with obesity vs controls; fronto-amygdalar effective connectivity during cognitive reappraisal as a function of BMI
- Obesityn = 48
- Controln = 54reference
- Outcome
- Fronto-amygdalar effective connectivity during reappraisal
Methodological detailsfunctional MRI, dynamic causal modeling, parametric empirical Bayes
- Functional MRI
- Dynamic causal modeling
- Parametric empirical Bayes
Main finding
As reported in the abstract
A top-down cortical model best explained the fMRI data (posterior probability)
86%
Further findings
| Outcome | P value |
|---|---|
| Difficulty in Emotion Regulation Scale scoresHigher with obesity | P < 0.001 |
Original publication
Dynamic fronto‐amygdalar interactions underlying emotion‐regulation deficits in women at higher weight. Obesity (Silver Spring). Published 6 August 2023. doi:10.
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