During an 18‐month course of automated insulin delivery treatment, children aged 2 to 6 years achieve and maintain a higher time in tight range
Authors' conclusion
Treatment with AID significantly increased TITR and TIR in young children. The positive effect of AID on glycaemic control observed after 6 months persisted throughout the 18 months of follow-up. Similarly, parental diabetes distress remained reduced during 18 months follow-up. These findings are reassuring and suggest that AID treatment improves glycaemic control and reduces parental diabetes distress in young children over an extended 18-month follow-up.
Study context
- Population
- Children aged 2 to 6 years treated with automated insulin delivery (AID), 2021–2023
- Participants
- 35 children
- Primary endpoint
- Changes in TIR, HbA1c, TAR, TITR (3.9-7.8 mmol/L) and mean sensor glucose value
- Follow-up
- 0, 6, 12 and 18 months
Methodological detailsnon-randomized, 18-month follow-up
- Non-randomized
- 18-month follow-up
Primary result
As reported in the abstract
TIR, TITR, HbA1c, mean sensor glucose, TAR · 0 to 6 months; through 18 months
- Time in range (TIR) and time in tight range (TITR) increased, and HbA1c, mean sensor glucose and time above range (TAR) decreased significantly between 0 and 6 months
- p < 0.001
Further findings
Parental diabetes distress (Problem Areas in Diabetes-Parent, revised (PAID-PR) score) · 0, 3 and 18 months
- PAID-PR mean score at 0 months
- 37.5
- PAID-PR mean score at 3 months
- 28.6 (p = 0.06)
- PAID-PR mean score at 18 months
- 24.6 (p < 0.001)
- PAID-PR score declined significantly between 3 and 18 months
Original publication
During an 18‐month course of automated insulin delivery treatment, children aged 2 to 6 years achieve and maintain a higher time in tight range. Diabetes Obes Metab. Published 21 March 2024. doi:10.
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